Two sample MR report
ELP5_Conventional Dendritic Cell against finn-b-ASTHMA_ALLERG_EXMORE
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 8 | 0.3333991 | 0.4495958 | 0.4863589 |
| Weighted median | 8 | -0.0873212 | 0.0230391 | 0.0001506 |
| Inverse variance weighted | 8 | -0.1065544 | 0.0171417 | 0.0000000 |
| Simple mode | 8 | -0.0859530 | 0.0342570 | 0.0404521 |
| Weighted mode | 8 | -0.0856649 | 0.0320075 | 0.0317040 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 2.028027 | 6 | 0.9171030 |
| Inverse variance weighted | 2.986988 | 7 | 0.8862033 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.29827 | 0.3045855 | 0.3652673 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0001244 | 0 | TRUE | 0.2967324 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
